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Chin augmentation with stem cell rich fat transfer. This woman had a prior facelift with another surgeon but was dissatisfied with her skin and the area around her mouth, particularly her lower face and chin. She wanted a long-term solution, but was not interested in any further surgery. This is the perfect situation to utilize fat transfer for long-term chin augmentation that will also improve skin quality. With chin augmentation, the contour, vertical height and width of the chin must be considered in the context of other aspects of the lower face such as the pre-jowl sulcus, marionette lines, and even the teeth, nose and lips to maintain balance, and especially for her to have an additive effect with her prior surgery. You can also appreciate the beautiful change in her skin quality in this region solely from the high concentration of adipocyte derived stem cells, which exert a positive effect on skin rejuvenation. Adipocyte derived stem cells have secretory factors that are effective in the treatment of UV induced wrinkles, with this anti-wrinkle effect mediated primarily by the reduction of UV induced programmed cell death (apoptosis) and the stimulation of collagen synthesis by dermal fibroblasts.